Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair–Deficient Colon Cancer
Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair–Deficient Colon Cancer
About this item
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Author / Creator
Chalabi, Myriam , Verschoor, Yara L. , Tan, Pedro Batista , Balduzzi, Sara , Van Lent, Anja U. , Grootscholten, Cecile , Dokter, Simone , Büller, Nikè V. , Grotenhuis, Brechtje A. , Kuhlmann, Koert , Burger, Jacobus W. , Huibregtse, Inge L. , Aukema, Tjeerd S. , Hendriks, Eduard R. , Oosterling, Steven J. , Snaebjornsson, Petur , Voest, Emile E. , Wessels, Lodewyk F. , Beets-Tan, Regina G. , Van Leerdam, Monique E. , Schumacher, Ton N. , van den Berg, José G. , Beets, Geerard L. and Haanen, John B.
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
Mismatch repair-deficient (dMMR) tumors can be found in 10 to 15% of patients with nonmetastatic colon cancer. In these patients, the efficacy of chemotherapy is limited. The use of neoadjuvant immunotherapy has shown promising results, but data from studies of this approach are limited.
We conducted a phase 2 study in which patients with nonmet...
Alternative Titles
Full title
Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair–Deficient Colon Cancer
Authors, Artists and Contributors
Author / Creator
Verschoor, Yara L.
Tan, Pedro Batista
Balduzzi, Sara
Van Lent, Anja U.
Grootscholten, Cecile
Dokter, Simone
Büller, Nikè V.
Grotenhuis, Brechtje A.
Kuhlmann, Koert
Burger, Jacobus W.
Huibregtse, Inge L.
Aukema, Tjeerd S.
Hendriks, Eduard R.
Oosterling, Steven J.
Snaebjornsson, Petur
Voest, Emile E.
Wessels, Lodewyk F.
Beets-Tan, Regina G.
Van Leerdam, Monique E.
Schumacher, Ton N.
van den Berg, José G.
Beets, Geerard L.
Haanen, John B.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3065275417
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3065275417
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2400634
