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Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazol...

Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazol...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3086066515

Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazole

About this item

Full title

Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazole

Publisher

New York: Springer US

Journal title

Pharmaceutical research, 2024-08, Vol.41 (8), p.1737-1754

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Purpose
The primary problem with climbazole (CLB), a broad-spectrum imidazole antifungal drug, is its low water solubility. In order to increase its water solubility and antifungal activity, three new multi-component crystals were synthesized in this work, and the intermolecular interactions were systematically studied. This work helps to optimi...

Alternative Titles

Full title

Multi-component Crystal Strategy for Improving Water Solubility and Antifungal Activity of Climbazole

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3086066515

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3086066515

Other Identifiers

ISSN

0724-8741,1573-904X

E-ISSN

1573-904X

DOI

10.1007/s11095-024-03748-5

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