MDM2 Is Essential to Maintain the Homeostasis of Epithelial Cells by Targeting p53
MDM2 Is Essential to Maintain the Homeostasis of Epithelial Cells by Targeting p53
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Author / Creator
Wang, Su , Zhong, Shufen , Huang, Ying , Zhu, Songling , Chen, Shuangfeng , Wang, Ran , Wangmo, Sonam , Peng, Bo , Lv, Houkun , Yang, Jichao , Ma, Liyan , Ling, Zhiyang , Zhang, Yaguang , Sui, Pengfei and Sun, Bing
Publisher
Basel, Switzerland: S. Karger AG
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Language
English
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Publisher
Basel, Switzerland: S. Karger AG
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Abstract
Introduction: MDM2 is known as the primary negative regulator of p53, and MDM2 promotes lung cancer fibrosis and lung injury through p53-dependent and p53-independent pathways. However, the mechanism by which MDM2 influences the pathogenesis of asthma is unknown. In this study, we investigated the function of MDM2 in lung epithelial cel...
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Full title
MDM2 Is Essential to Maintain the Homeostasis of Epithelial Cells by Targeting p53
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TN_cdi_proquest_miscellaneous_3092368269
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3092368269
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ISSN
1662-811X,1662-8128
E-ISSN
1662-8128
DOI
10.1159/000539824
