Renin angiotensin system inhibitors and outcome in patients with takotsubo syndrome: A propensity sc...
Renin angiotensin system inhibitors and outcome in patients with takotsubo syndrome: A propensity score analysis of the GEIST registry
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Author / Creator
Santoro, Francesco , Stiermaier, Thomas , Núñez Gil, Iván J. , El-Battrawy, Ibrahim , Pätz, Toni , Cacciotti, Luca , Guerra, Federico , Novo, Giuseppina , Musumeci, Beatrice , Volpe, Massimo , Mariano, Enrica , Caldarola, Pasquale , Montisci, Roberta , Ragnatela, Ilaria , Cetera, Rosa , Vazirani, Ravi , Lluch, Carmen , Uribarri, Aitor , Corbi-Pascual, Miguel , Conty Cardona, David Aritza , Akin, Ibrahim , Barbato, Emanuele , Thiele, Holger , Brunetti, Natale Daniele , Eitel, Ingo and Arcari, Luca
Publisher
United States: Elsevier Inc
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Language
English
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Publisher
United States: Elsevier Inc
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Scope and Contents
Contents
Few data are available on long-term drug therapy and its potential prognostic impact after Takotsubo syndrome (TTS). Aim of the study is to evaluate clinical characteristics and long-term outcome of TTS patients on Renin Angiotensin system inhibitors (RASi).
TTS patients were enrolled in the international multicenter GEIST (GErman Italian Spanish Takotsubo) registry. Median follow-up was 31 (Interquartile range 12-56) months. Comparison of RASi treated vs. untreated patients was performed within the overall population and after 1:1 propensity score matching for age, sex, comorbidities, type of trigger and in-hospital complications.
clinicaltrials.gov, NCT04361994, https://clinicaltrials.gov/study/NCT04361994
Of the 2453 TTS patients discharged alive, 1683 (68%) received RASi therapy. Patients with RASi were older (age 71 ± 11 vs 69 ± 13 years, P = .01), with higher prevalence of hypertension (74% vs 53%, P < .01) and diabetes (19% v s15%, P = .01), higher admission left ventricular ejection fraction (LVEF) (41 ± 11% vs 39 ± 12%, P < .01) and lo...
Alternative Titles
Full title
Renin angiotensin system inhibitors and outcome in patients with takotsubo syndrome: A propensity score analysis of the GEIST registry
Authors, Artists and Contributors
Author / Creator
Stiermaier, Thomas
Núñez Gil, Iván J.
El-Battrawy, Ibrahim
Pätz, Toni
Cacciotti, Luca
Guerra, Federico
Novo, Giuseppina
Musumeci, Beatrice
Volpe, Massimo
Mariano, Enrica
Caldarola, Pasquale
Montisci, Roberta
Ragnatela, Ilaria
Cetera, Rosa
Vazirani, Ravi
Lluch, Carmen
Uribarri, Aitor
Corbi-Pascual, Miguel
Conty Cardona, David Aritza
Akin, Ibrahim
Barbato, Emanuele
Thiele, Holger
Brunetti, Natale Daniele
Eitel, Ingo
Arcari, Luca
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3103445231
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3103445231
Other Identifiers
ISSN
0002-8703,1097-6744
E-ISSN
1097-6744
DOI
10.1016/j.ahj.2024.08.019
