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Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension throu...

Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension throu...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3115771218

Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling

About this item

Full title

Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling

Publisher

New York: Springer US

Journal title

Apoptosis (London), 2024-12, Vol.29 (11-12), p.2161-2182

Language

English

Formats

Publication information

Publisher

New York: Springer US

More information

Scope and Contents

Contents

Myocardial fibrosis is a typical pathological manifestation of hypertension. However, the exact role of sirtuin 7 (SIRT7) in myocardial remodeling remains largely unclear. Here, spontaneously hypertensive rats (SHRs) and angiotensin (Ang) II-induced hypertensive mice were pretreated with recombinant adeno-associated virus (rAAV)-SIRT7, copper chela...

Alternative Titles

Full title

Sirtuin 7 ameliorates cuproptosis, myocardial remodeling and heart dysfunction in hypertension through the modulation of YAP/ATP7A signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3115771218

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3115771218

Other Identifiers

ISSN

1360-8185,1573-675X

E-ISSN

1573-675X

DOI

10.1007/s10495-024-02021-9

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