APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease
APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease
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United States: Massachusetts Medical Society
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Language
English
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United States: Massachusetts Medical Society
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To the Editor:
The report by Quiroz et al. (June 20 issue)
1
on the Colombian
PSEN1
E280A
pedigree suggests a protective effect of apolipoprotein E3 Christchurch (
APOE3
Ch
) variant heterozygosity. The signal from 27 carriers is driven by 13 carriers in whom mild cognitive impairment or dementia developed. A previous stu...
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Full title
APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer’s Disease
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TN_cdi_proquest_miscellaneous_3122638922
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3122638922
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ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMc2409320