Development of a novel radioiodinated compound for amyloid and tau deposition imaging in Alzheimer's...
Development of a novel radioiodinated compound for amyloid and tau deposition imaging in Alzheimer's disease and tauopathy mouse models
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Publisher
United States: Elsevier Inc
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English
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United States: Elsevier Inc
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•We have successfully developed a novel SPECT ligand 123/125I-AD-DRK for cheaper diagnostic nuclear medicine imaging of AD and/or non-AD tauopathies.•123/125I-AD-DRK can bind to amyloid and tau aggregates deposited in postmortem brains from the patients with AD and PSP, respectively.•123/125I-AD-DRK can visualize mature amyloid and tau aggregates i...
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Development of a novel radioiodinated compound for amyloid and tau deposition imaging in Alzheimer's disease and tauopathy mouse models
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TN_cdi_proquest_miscellaneous_3131851533
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3131851533
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ISSN
1053-8119,1095-9572
E-ISSN
1095-9572
DOI
10.1016/j.neuroimage.2024.120947
