Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia
Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia
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Full title
Author / Creator
Roddie, Claire , Sandhu, Karamjeet S. , Tholouli, Eleni , Logan, Aaron C. , Shaughnessy, Paul , Barba, Pere , Ghobadi, Armin , Guerreiro, Manuel , Yallop, Deborah , Abedi, Mehrdad , Pantin, Jeremy M. , Yared, Jean A. , Beitinjaneh, Amer M. , Chaganti, Sridhar , Hodby, Katharine , Menne, Tobias , Arellano, Martha L. , Malladi, Ram , Shah, Bijal D. , Mountjoy, Luke , O’Dwyer, Kristen M. , Peggs, Karl S. , Lao-Sirieix, Pierre , Zhang, Yiyun , Brugger, Wolfram , Braendle, Edgar , Pule, Martin , Bishop, Michael R. , DeAngelo, Daniel J. , Park, Jae H. and Jabbour, Elias
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
A CD19-specific CAR T-cell therapy with intermediate affinity for CD19 produced a response in 77% of adults with refractory disease. Overall survival was 61% at 12 months, and serious toxic effects were rare.
Alternative Titles
Full title
Obecabtagene Autoleucel in Adults with B-Cell Acute Lymphoblastic Leukemia
Authors, Artists and Contributors
Author / Creator
Sandhu, Karamjeet S.
Tholouli, Eleni
Logan, Aaron C.
Shaughnessy, Paul
Barba, Pere
Ghobadi, Armin
Guerreiro, Manuel
Yallop, Deborah
Abedi, Mehrdad
Pantin, Jeremy M.
Yared, Jean A.
Beitinjaneh, Amer M.
Chaganti, Sridhar
Hodby, Katharine
Menne, Tobias
Arellano, Martha L.
Malladi, Ram
Shah, Bijal D.
Mountjoy, Luke
O’Dwyer, Kristen M.
Peggs, Karl S.
Lao-Sirieix, Pierre
Zhang, Yiyun
Brugger, Wolfram
Braendle, Edgar
Pule, Martin
Bishop, Michael R.
DeAngelo, Daniel J.
Park, Jae H.
Jabbour, Elias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3133733887
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3133733887
Other Identifiers
ISSN
0028-4793,1533-4406
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2406526