Caffeine's Neuroprotective Effect on Memory Impairment: Suppression of Adenosine A2A Receptor and En...
Caffeine's Neuroprotective Effect on Memory Impairment: Suppression of Adenosine A2A Receptor and Enhancement of Tyrosine Hydroxylase in Dopaminergic Neurons Under Hypobaric Hypoxia Conditions
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Author / Creator
Zhong, Zhifeng , Dong, Huaping , Zhou, Simin , Lin, Chaoqun , Huang, Pei , Li, Xiaoxu , Zhang, Jijian , Xie, Jiaxin , Wu, Yu and Li, Peng
Publisher
Oxford: John Wiley & Sons, Inc
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Language
English
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Publisher
Oxford: John Wiley & Sons, Inc
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ABSTRACT
Aims
Chronic hypobaric hypoxia frequently results in memory deficits, with severe cases showing marked alterations in dopamine levels and its metabolites. This research explores caffeine's modulation of the adenosine A2A receptor (A2AR) and its regulatory effects on tyrosine hydroxylase (TH), aiming to restore dopamine homeostasis an...
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Full title
Caffeine's Neuroprotective Effect on Memory Impairment: Suppression of Adenosine A2A Receptor and Enhancement of Tyrosine Hydroxylase in Dopaminergic Neurons Under Hypobaric Hypoxia Conditions
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Record Identifier
TN_cdi_proquest_miscellaneous_3146670799
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3146670799
Other Identifiers
ISSN
1755-5930,1755-5949
E-ISSN
1755-5949
DOI
10.1111/cns.70134