Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord...
Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: a randomised, double-blind, multicentre, placebo-controlled, phase 2b trial
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Author / Creator
Weidner, Norbert , Abel, Rainer , Maier, Doris , Röhl, Klaus , Röhrich, Frank , Baumberger, Michael , Hund-Georgiadis, Margret , Saur, Marion , Benito-Penalva, Jesús , Rehahn, Kerstin , Aach, Mirko , Badke, Andreas , Kriz, Jiri , Barkovits, Katalin , Killeen, Tim , Farner, Lynn , Seif, Maryam , Hubli, Michèle , Marcus, Katrin , Maurer, Michael A , Robert, Bérénice , Rupp, Rüdiger , Scheuren, Paulina S , Schubert, Martin , Schuld, Christian , Sina, Christina , Steiner, Bettina , Weis, Tanja , Hug, Andreas , Bolliger, Marc , Weiskopf, Nikolaus , Freund, Patrick , Hothorn, Torsten , Schwab, Martin E , Curt, Armin and Nogo Inhibition in Spinal Cord Injury Study Group
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Spinal cord injury results in permanent neurological impairment and disability due to the absence of spontaneous regeneration. NG101, a recombinant human antibody, neutralises the neurite growth-inhibiting protein Nogo-A, promoting neural repair and motor recovery in animal models of spinal cord injury. We aimed to evaluate the efficacy of intrathe...
Alternative Titles
Full title
Safety and efficacy of intrathecal antibodies to Nogo-A in patients with acute cervical spinal cord injury: a randomised, double-blind, multicentre, placebo-controlled, phase 2b trial
Authors, Artists and Contributors
Author / Creator
Abel, Rainer
Maier, Doris
Röhl, Klaus
Röhrich, Frank
Baumberger, Michael
Hund-Georgiadis, Margret
Saur, Marion
Benito-Penalva, Jesús
Rehahn, Kerstin
Aach, Mirko
Badke, Andreas
Kriz, Jiri
Barkovits, Katalin
Killeen, Tim
Farner, Lynn
Seif, Maryam
Hubli, Michèle
Marcus, Katrin
Maurer, Michael A
Robert, Bérénice
Rupp, Rüdiger
Scheuren, Paulina S
Schubert, Martin
Schuld, Christian
Sina, Christina
Steiner, Bettina
Weis, Tanja
Hug, Andreas
Bolliger, Marc
Weiskopf, Nikolaus
Freund, Patrick
Hothorn, Torsten
Schwab, Martin E
Curt, Armin
Nogo Inhibition in Spinal Cord Injury Study Group
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3147973186
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3147973186
Other Identifiers
ISSN
1474-4422,1474-4465
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(24)00447-2