Vaccine-associated respiratory pathology correlates with viral clearance and protective immunity aft...
Vaccine-associated respiratory pathology correlates with viral clearance and protective immunity after immunization with self-amplifying RNA expressing the spike (S) protein of SARS-CoV-2 in mouse models
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Publisher
Netherlands: Elsevier Ltd
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Language
English
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Publisher
Netherlands: Elsevier Ltd
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Scope and Contents
Contents
Highlights•saRNA vaccines for SARS-CoV-2: Protection & Pathology in mice. •Post-challenge lung pathology in vaccinated mice linked to T- and B-cell infiltration. •T-cell depletion reduces pathology but delays virus clearance.
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Full title
Vaccine-associated respiratory pathology correlates with viral clearance and protective immunity after immunization with self-amplifying RNA expressing the spike (S) protein of SARS-CoV-2 in mouse models
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TN_cdi_proquest_miscellaneous_3153177548
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153177548
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ISSN
0264-410X
E-ISSN
1873-2518
DOI
10.1016/j.vaccine.2023.12.052