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Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germli...

Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germli...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153562726

Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germline variants of unknown significance (VUS) in BRCA1 and BRCA2 genes

About this item

Full title

Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germline variants of unknown significance (VUS) in BRCA1 and BRCA2 genes

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

Journal title

Cancer chemotherapy and pharmacology, 2023-12, Vol.92 (6), p.501-510

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer Berlin Heidelberg

More information

Scope and Contents

Contents

Purpose
The clinical outcome and the efficacy of chemotherapy in pancreatic cancer patients with BRCA1/2 Variants of Unknown Significance (VUS) is unknown. We explored the effects of chemotherapy with or without Platinum in non metastatic and metastatic pancreatic cancer patients with BRCA1/2 VUS.
Methods
A retrospective analysis of non-me...

Alternative Titles

Full title

Clinical outcomes and response to chemotherapy in a cohort of pancreatic cancer patients with germline variants of unknown significance (VUS) in BRCA1 and BRCA2 genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3153562726

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153562726

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-023-04585-w

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