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Systematic biases in DNA copy number originate from isolation procedures

Systematic biases in DNA copy number originate from isolation procedures

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153567036

Systematic biases in DNA copy number originate from isolation procedures

About this item

Full title

Systematic biases in DNA copy number originate from isolation procedures

Publisher

England: BioMed Central Ltd

Journal title

Genome Biology (Online Edition), 2013-04, Vol.14 (4), p.R33-R33, Article R33

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

The ability to accurately detect DNA copy number variation in both a sensitive and quantitative manner is important in many research areas. However, genome-wide DNA copy number analyses are complicated by variations in detection signal.
While GC content has been used to correct for this, here we show that coverage biases are tissue-specific and...

Alternative Titles

Full title

Systematic biases in DNA copy number originate from isolation procedures

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3153567036

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153567036

Other Identifiers

ISSN

1474-760X

E-ISSN

1474-760X

DOI

10.1186/gb-2013-14-4-r33

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