Systematic biases in DNA copy number originate from isolation procedures
Systematic biases in DNA copy number originate from isolation procedures
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
The ability to accurately detect DNA copy number variation in both a sensitive and quantitative manner is important in many research areas. However, genome-wide DNA copy number analyses are complicated by variations in detection signal.
While GC content has been used to correct for this, here we show that coverage biases are tissue-specific and...
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Systematic biases in DNA copy number originate from isolation procedures
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TN_cdi_proquest_miscellaneous_3153567036
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153567036
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ISSN
1474-760X
E-ISSN
1474-760X
DOI
10.1186/gb-2013-14-4-r33