Novel Genome-Engineered H Alleles Differentially Affect Lateral Inhibition and Cell Dichotomy Proces...
Novel Genome-Engineered H Alleles Differentially Affect Lateral Inhibition and Cell Dichotomy Processes during Bristle Organ Development
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Publisher
Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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Hairless (H) encodes the major antagonist in the Notch signaling pathway, which governs cellular differentiation of various tissues in Drosophila. By binding to the Notch signal transducer Suppressor of Hairless (Su(H)), H assembles repressor complexes onto Notch target genes. Using genome engineering, three new H alleles, HFA, HLLAA and HWA were g...
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Full title
Novel Genome-Engineered H Alleles Differentially Affect Lateral Inhibition and Cell Dichotomy Processes during Bristle Organ Development
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TN_cdi_proquest_miscellaneous_3153588577
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153588577
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ISSN
2073-4425
E-ISSN
2073-4425
DOI
10.3390/genes15050552
