Methotrexate Polyglutamate Concentrations as a Possible Predictive Marker for Effectiveness of Metho...
Methotrexate Polyglutamate Concentrations as a Possible Predictive Marker for Effectiveness of Methotrexate Therapy in Patients with Sarcoidosis: A Pilot Study
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New York: Springer US
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English
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New York: Springer US
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Introduction
Methotrexate (MTX), a folate antagonist, is often used as second-line treatment in patients with sarcoidosis. Effectiveness of MTX has large inter-patient variability and at present therapeutic drug monitoring (TDM) of MTX is not possible. Upon administration, MTX is actively transported into cells and metabolized to its active form...
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Methotrexate Polyglutamate Concentrations as a Possible Predictive Marker for Effectiveness of Methotrexate Therapy in Patients with Sarcoidosis: A Pilot Study
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TN_cdi_proquest_miscellaneous_3153611377
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153611377
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ISSN
0341-2040
E-ISSN
1432-1750
DOI
10.1007/s00408-023-00656-0
