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A novel Candida albicans Als3, Hwp1 and Met6 derived complex peptide protects mice against hematogen...

A novel Candida albicans Als3, Hwp1 and Met6 derived complex peptide protects mice against hematogen...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153768903

A novel Candida albicans Als3, Hwp1 and Met6 derived complex peptide protects mice against hematogenously induced candidiasis

About this item

Full title

A novel Candida albicans Als3, Hwp1 and Met6 derived complex peptide protects mice against hematogenously induced candidiasis

Publisher

Netherlands: Elsevier Ltd

Journal title

Vaccine, 2024-08, Vol.42 (20), p.125990-125990, Article 125990

Language

English

Formats

Publication information

Publisher

Netherlands: Elsevier Ltd

More information

Scope and Contents

Contents

Highlights•3P-KLH peptide (Als3, Hwp1, Met6) protects against systemic candidiasis in mice. •Immunized mice showed significantly lower fungal load in kidneys than control group. •37.5 % of immunized mice survived 21 days post-infection, controls died within 9 days. •The study highlights the potential of multi-epitope presentation as a vaccine desig...

Alternative Titles

Full title

A novel Candida albicans Als3, Hwp1 and Met6 derived complex peptide protects mice against hematogenously induced candidiasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3153768903

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153768903

Other Identifiers

ISSN

0264-410X,1873-2518

E-ISSN

1873-2518

DOI

10.1016/j.vaccine.2024.05.038

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