Structure Characterization of Zinc Finger Motif 1 and 2 of GLI1 DNA Binding Region
Structure Characterization of Zinc Finger Motif 1 and 2 of GLI1 DNA Binding Region
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Switzerland: MDPI AG
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English
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Switzerland: MDPI AG
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As a transcription factor, GLI1 plays an important role in cell cycle regulation, DNA replication, and DNA damage responses. The aberrant activation of GLI1 has been associated with cancers such as glioma, osteosarcoma, and rhabdomyosarcoma. The binding of GLI1 to a specific DNA sequence was achieved by five tandem zinc finger motifs (Zif motifs) o...
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Structure Characterization of Zinc Finger Motif 1 and 2 of GLI1 DNA Binding Region
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TN_cdi_proquest_miscellaneous_3153871283
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153871283
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ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms252413368
