Claudin 18.2-targeting antibody–drug conjugate CMG901 in patients with advanced gastric or gastro-oe...
Claudin 18.2-targeting antibody–drug conjugate CMG901 in patients with advanced gastric or gastro-oesophageal junction cancer (KYM901): a multicentre, open-label, single-arm, phase 1 trial
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Author / Creator
Ruan, Dan-Yun, MD , Liu, Fu-Rong, MD , Wei, Xiao-Li, MD , Luo, Su-Xia, Prof , Zhuang, Zhi-Xiang, Prof , Wang, Zhen-Ning, Prof , Liu, Fu-Nan, Prof , Zhang, Yan-Qiao, Prof , Yang, Jian-Wei, BS , Chen, Zhen-Dong, Prof , Wang, Yong-Sheng, Prof , Wang, Jun-Ye, Prof , Liang, Xiao-Hua, Prof , Wu, Xiao-Jie, Prof , Zheng, Yu-Long, Prof , Liu, Jian, Prof , Shi, Xi, Prof , Kumar, Rakesh, PhD , Liu, Wei, PhD , Chen, Bo, PhD , Zhang, Dong-Sheng, Prof and Xu, Rui-Hua, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Scope and Contents
Contents
SummaryBackgroundCMG901 is a novel first-in-class antibody–drug conjugate with a humanised anticlaudin 18.2 antibody linked to microtubule-disrupting agent monomethyl auristatin E. We aimed to assess the antitumour activity and safety of CMG901 in patients with advanced gastric or gastro-oesophageal junction cancer and other solid tumours. MethodsK...
Alternative Titles
Full title
Claudin 18.2-targeting antibody–drug conjugate CMG901 in patients with advanced gastric or gastro-oesophageal junction cancer (KYM901): a multicentre, open-label, single-arm, phase 1 trial
Authors, Artists and Contributors
Author / Creator
Liu, Fu-Rong, MD
Wei, Xiao-Li, MD
Luo, Su-Xia, Prof
Zhuang, Zhi-Xiang, Prof
Wang, Zhen-Ning, Prof
Liu, Fu-Nan, Prof
Zhang, Yan-Qiao, Prof
Yang, Jian-Wei, BS
Chen, Zhen-Dong, Prof
Wang, Yong-Sheng, Prof
Wang, Jun-Ye, Prof
Liang, Xiao-Hua, Prof
Wu, Xiao-Jie, Prof
Zheng, Yu-Long, Prof
Liu, Jian, Prof
Shi, Xi, Prof
Kumar, Rakesh, PhD
Liu, Wei, PhD
Chen, Bo, PhD
Zhang, Dong-Sheng, Prof
Xu, Rui-Hua, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3153915520
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3153915520
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ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(24)00636-3