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Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Pri...

Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Pri...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3163847679

Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Primary Alveolar Type II Cells

About this item

Full title

Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Primary Alveolar Type II Cells

Publisher

United States

Journal title

Aging and disease, 2025-01

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Homeostatic imbalance and lung function decline are central physiological characteristics of aging and susceptibility to respiratory diseases. Senescence contributes to tissue damage and alveolar epithelial cell injury and decreases reparative capacity. Alveolar type II (ATII) cells have stem cell potential and self-renew to regenerate the alveoli...

Alternative Titles

Full title

Age-Associated Activation of the cGAS-STING Pathway and Impairment of DNA Damage Repair in Human Primary Alveolar Type II Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3163847679

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3163847679

Other Identifiers

ISSN

2152-5250

E-ISSN

2152-5250

DOI

10.14336/AD.2024.1175

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