CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-A...
CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages
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Author / Creator
Xiong, Jiaqiang , Huang, Juyuan , Xu, Hanxiao , Wu, Qiuji , Zhao, Jiahui , Chen, Yurou , Fan, Guanlan , Guan, Haotong , Xiao, Rourou , He, Zhaojin , Wu, Siqi , Ouyang, Wenliang , Wang, Shixuan , Zhang, Lu , Xia, Peng , Zhang, Wei and Wu, Meng
Publisher
Germany
Journal title
Language
English
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Publisher
Germany
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Scope and Contents
Contents
CpG oligodeoxynucleotides (CpG), as an immunoadjuvant, can facilitate the transformation of tumor-associated macrophages (TAMs)into tumoricidal M1 macrophages. However, the accumulation of free CpG in tumor tissues remains a substantial challenge. To address this, a nanovaccine (PLGA-CpG@ID8-M) is engineered by encapsulating CpG within PLGA using I...
Alternative Titles
Full title
CpG-Based Nanovaccines Enhance Ovarian Cancer Immune Response by Gbp2-Mediated Remodeling of Tumor-Associated Macrophages
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3169794936
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3169794936
Other Identifiers
ISSN
2198-3844
E-ISSN
2198-3844
DOI
10.1002/advs.202412881
