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A Xanthine Derivative With Novel Heat Shock Protein 90-Alpha Inhibitory and Senolytic Properties

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A Xanthine Derivative With Novel Heat Shock Protein 90-Alpha Inhibitory and Senolytic Properties

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3178295942

A Xanthine Derivative With Novel Heat Shock Protein 90-Alpha Inhibitory and Senolytic Properties

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Publication information

Publisher

England

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Scope and Contents

Contents

The accumulation of senescent cells contributes to aging and related diseases; therefore, discovering safe senolytic agents-compounds that selectively eliminate senescent cells-is a critical priority. Heat shock protein 90 (HSP90) inhibitors (HSP90i), traditionally investigated for cancer treatment, have shown potential as senolytic agents. However...

Alternative Titles

Full title

A Xanthine Derivative With Novel Heat Shock Protein 90-Alpha Inhibitory and Senolytic Properties

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Author / Creator

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Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3178295942

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3178295942

Other Identifiers

ISSN

1474-9718,1474-9726

E-ISSN

1474-9726

DOI

10.1111/acel.70047

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