First-line talazoparib plus enzalutamide versus placebo plus enzalutamide in men with metastatic cas...
First-line talazoparib plus enzalutamide versus placebo plus enzalutamide in men with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: patient-reported outcomes from the randomised, double-blind, placebo-controlled, phase 3 TALAPRO-2 trial
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Author / Creator
Fay, Andre P, Prof , Fizazi, Karim, Prof , Matsubara, Nobuaki, MD , Azad, Arun A, Prof , Saad, Fred, Prof , De Giorgi, Ugo, MD , Joung, Jae Young, Prof , Fong, Peter C C, MD , Jones, Robert J, Prof , Zschäbitz, Stefanie, MD , Oldenburg, Jan, Prof , Shore, Neal D, MD , Dunshee, Curtis, MD , Carles, Joan, MD , Cislo, Paul, PhD , Chang, Jane, MPH , Healy, Cynthia G, BS , Niyazov, Alexander, PharmD and Agarwal, Neeraj, Prof
Publisher
England: Elsevier Ltd
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Language
English
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Publisher
England: Elsevier Ltd
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Contents
SummaryBackgroundIn the phase 3 TALAPRO-2 trial, talazoparib plus enzalutamide significantly improved radiographic progression-free survival compared with placebo plus enzalutamide in men with metastatic castration-resistant prostate cancer harbouring alterations in genes involved in homologous recombination repair (HRR). We aimed to assess patient...
Alternative Titles
Full title
First-line talazoparib plus enzalutamide versus placebo plus enzalutamide in men with metastatic castration-resistant prostate cancer and homologous recombination repair gene alterations: patient-reported outcomes from the randomised, double-blind, placebo-controlled, phase 3 TALAPRO-2 trial
Authors, Artists and Contributors
Author / Creator
Fizazi, Karim, Prof
Matsubara, Nobuaki, MD
Azad, Arun A, Prof
Saad, Fred, Prof
De Giorgi, Ugo, MD
Joung, Jae Young, Prof
Fong, Peter C C, MD
Jones, Robert J, Prof
Zschäbitz, Stefanie, MD
Oldenburg, Jan, Prof
Shore, Neal D, MD
Dunshee, Curtis, MD
Carles, Joan, MD
Cislo, Paul, PhD
Chang, Jane, MPH
Healy, Cynthia G, BS
Niyazov, Alexander, PharmD
Agarwal, Neeraj, Prof
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Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_3186350932
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3186350932
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ISSN
1470-2045,1474-5488
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(25)00031-2
