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Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutroph...

Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutroph...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3194256432

Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR

About this item

Full title

Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR

Publisher

England

Journal title

eLife, 2025-04, Vol.14

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Monomethyl fumarate (MMF) and its prodrug dimethyl fumarate (DMF) are currently the most widely used agents for the treatment of multiple sclerosis (MS). However, not all patients benefit from DMF. We hypothesized that the variable response of patients may be due to their diet. In support of this hypothesis, mice subjected to experimental autoimmun...

Alternative Titles

Full title

Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3194256432

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3194256432

Other Identifiers

ISSN

2050-084X

E-ISSN

2050-084X

DOI

10.7554/eLife.98970

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