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Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxi...

Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxi...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3202401621

Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells

About this item

Full title

Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells

Publisher

England

Journal title

Journal of translational medicine, 2025-05, Vol.23 (1), p.523

Language

English

Formats

Publication information

Publisher

England

More information

Scope and Contents

Contents

Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular tone, endothelial function, and inflammation. Our objectives were to identify proteins specifically secreted by f...

Alternative Titles

Full title

Reduced blood EPAC1 protein levels as a marker of severe coronary artery disease: the role of hypoxic foam cell-transformed smooth muscle cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3202401621

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3202401621

Other Identifiers

ISSN

1479-5876

E-ISSN

1479-5876

DOI

10.1186/s12967-025-06513-3

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