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Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis-induc...

Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis-induc...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3206595305

Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis-induced cytokine transcriptional responses

About this item

Full title

Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis-induced cytokine transcriptional responses

Publisher

United States

Journal title

The Journal of clinical investigation, 2025-05

Language

English

Formats

Publication information

Publisher

United States

More information

Scope and Contents

Contents

Immune and clinical outcomes to Mycobacterium tuberculosis (Mtb) infection vary greatly between individuals yet the underlying genetic and cellular mechanisms driving this heterogeneity remain poorly understood. We performed a cellular genome-wide association study (GWAS) to identify genetic variants associated with Mtb-induced monocyte transcripti...

Alternative Titles

Full title

Myeloid cell genome-wide screen identifies variants associated with Mycobacterium tuberculosis-induced cytokine transcriptional responses

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_3206595305

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_3206595305

Other Identifiers

ISSN

1558-8238

E-ISSN

1558-8238

DOI

10.1172/JCI179822

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