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Defining a Link with Asthma in Mice Congenitally Deficient in Eosinophils

Defining a Link with Asthma in Mice Congenitally Deficient in Eosinophils

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_35138912

Defining a Link with Asthma in Mice Congenitally Deficient in Eosinophils

About this item

Full title

Defining a Link with Asthma in Mice Congenitally Deficient in Eosinophils

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2004-09, Vol.305 (5691), p.1773-1776

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Eosinophils are often dominant inflammatory cells present in the lungs of asthma patients. Nonetheless, the role of these leukocytes remains poorly understood. We have created a transgenic line of mice (PHIL) that are specifically devoid of eosinophils, but otherwise have a full complement of hematopoietically derived cells. Allergen challenge of P...

Alternative Titles

Full title

Defining a Link with Asthma in Mice Congenitally Deficient in Eosinophils

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_35138912

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_35138912

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1099472

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