Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
About this item
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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More information
Scope and Contents
Contents
Hepatocellular carcinoma (HCC), the most common liver cancer, occurs mainly in men. Similar gender disparity is seen in mice given a chemical carcinogen, diethylnitrosamine (DEN). DEN administration caused greater increases in serum interleukin-6 (IL-6) concentration in males than it did in females. Furthermore, ablation of IL-6 abolished the gende...
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Full title
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
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Record Identifier
TN_cdi_proquest_miscellaneous_35190564
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_35190564
Other Identifiers
ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1140485
