A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity
A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity
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Washington, DC: American Association for the Advancement of Science
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English
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Washington, DC: American Association for the Advancement of Science
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Contents
Synonymous single-nucleotide polymorphisms (SNPs) do not produce altered coding sequences, and therefore they are not expected to change the function of the protein in which they occur. We report that a synonymous SNP in the Multidrug Resistance 1 (MDR1) gene, part of a haplotype previously linked to altered function of the MDR1 gene product P-glyc...
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Full title
A "Silent" Polymorphism in the MDR1 Gene Changes Substrate Specificity
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TN_cdi_proquest_miscellaneous_36218815
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_36218815
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ISSN
0036-8075
E-ISSN
1095-9203
DOI
10.1126/science.1135308
