Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor...
Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor antagonists in cancer patients
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Publisher
Berlin: Springer
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Language
English
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Publisher
Berlin: Springer
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Contents
The aim of this study was to determine the usefulness of receptor occupancy theory-based analysis using pharmacokinetic and pharmacodynamic parameters for predicting the average receptor occupancy (PhiB) in humans of each of five 5-HT3 antagonists administered at standard doses.
The relationship between the PhiB value and the complete vomiting i...
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Full title
Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor antagonists in cancer patients
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TN_cdi_proquest_miscellaneous_66673834
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66673834
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ISSN
0344-5704
E-ISSN
1432-0843
DOI
10.1007/s00280-004-0798-x