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Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor...

Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66673834

Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor antagonists in cancer patients

About this item

Full title

Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor antagonists in cancer patients

Publisher

Berlin: Springer

Journal title

Cancer chemotherapy and pharmacology, 2004-08, Vol.54 (2), p.185-190

Language

English

Formats

Publication information

Publisher

Berlin: Springer

More information

Scope and Contents

Contents

The aim of this study was to determine the usefulness of receptor occupancy theory-based analysis using pharmacokinetic and pharmacodynamic parameters for predicting the average receptor occupancy (PhiB) in humans of each of five 5-HT3 antagonists administered at standard doses.
The relationship between the PhiB value and the complete vomiting i...

Alternative Titles

Full title

Receptor occupancy theory-based analysis of antiemetic effects and standard doses of 5-HT3 receptor antagonists in cancer patients

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66673834

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66673834

Other Identifiers

ISSN

0344-5704

E-ISSN

1432-0843

DOI

10.1007/s00280-004-0798-x

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