Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplasti...
Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma
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England
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English
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England
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Nucleophosmin-anaplastic lymphoma kinase (NPM-ALK) is an aberrant fusion gene product expressed in a subset of cases of anaplastic large cell lymphoma (ALCL). It has been shown that NPM-ALK binds to and activates signal transducer and activator of transcription 3 (STAT3) in vitro, and that STAT3 is constitutively active in ALK(+) ALCL cell lines an...
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Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma
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TN_cdi_proquest_miscellaneous_66709212
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66709212
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ISSN
0950-9232
DOI
10.1038/sj.onc.1207703
