Cytochrome P450 2c9 phenotyping using low-dose tolbutamide
Cytochrome P450 2c9 phenotyping using low-dose tolbutamide
About this item
Full title
Author / Creator
Publisher
Heidelberg: Springer
Journal title
Language
English
Formats
Publication information
Publisher
Heidelberg: Springer
Subjects
More information
Scope and Contents
Contents
The hypoglycaemic drug tolbutamide is used for assessment of CYP2C9 activity in vivo. However, therapeutically active doses of 500 mg bear the risk of hypoglycaemia, and a tolbutamide-derived parameter based on a single plasma or urine concentration reflecting CYP2C9 activity accurately is lacking.
We examined tolbutamide and its metabolites 4'-...
Alternative Titles
Full title
Cytochrome P450 2c9 phenotyping using low-dose tolbutamide
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_66732522
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66732522
Other Identifiers
ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-004-0754-z
