Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly understood. The chemokine stromal cell–derived factor-1 (SDF-1 or CXCL12) mediates homing of stem cells to bone marrow by binding to CXCR4 on circulating cells
1
,
2
. SDF-1 and CXCR4 are expressed in complementary patterns during embryonic orga...
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Full title
Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1
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TN_cdi_proquest_miscellaneous_66764645
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66764645
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/nm1075