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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66764645

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

About this item

Full title

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2004-08, Vol.10 (8), p.858-864

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

The trafficking of circulating stem and progenitor cells to areas of tissue damage is poorly understood. The chemokine stromal cell–derived factor-1 (SDF-1 or CXCL12) mediates homing of stem cells to bone marrow by binding to CXCR4 on circulating cells
1
,
2
. SDF-1 and CXCR4 are expressed in complementary patterns during embryonic orga...

Alternative Titles

Full title

Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66764645

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66764645

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm1075

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