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Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interfer...

Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interfer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66771228

Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma)

About this item

Full title

Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma)

Publisher

United States: Mary Ann Liebert, Inc

Journal title

Journal of interferon & cytokine research, 2004-07, Vol.24 (7), p.388-390

Language

English

Formats

Publication information

Publisher

United States: Mary Ann Liebert, Inc

More information

Scope and Contents

Contents

We sought to investigate the anti-severe acute respiratory syndrome (SARS)-associated coronavirus (SCoV) activities of type I (alpha and beta) and type II (gamma) interferons (IFN) in vitro. Type I IFNs protected cells from cytopathic effects (CPE) induced by SCoV, and inhibited viral genomic RNA replication in FRhk-4 cells (measured by quantitativ...

Alternative Titles

Full title

Potent inhibition of SARS-associated coronavirus (SCOV) infection and replication by type I interferons (IFN-alpha/beta) but not by type II interferon (IFN-gamma)

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66771228

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66771228

Other Identifiers

ISSN

1079-9907

E-ISSN

1557-7465

DOI

10.1089/1079990041535610

How to access this item