Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of seri...
Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375
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England
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English
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England
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Morphine is a poor inducer of micro-opioid receptor (MOR) internalization, but a potent inducer of cellular tolerance. Here we show that, in contrast to full agonists such as [D-Ala(2)-MePhe(4)-Gly-ol]enkephalin (DAMGO), morphine stimulated a selective phosphorylation of the carboxy-terminal residue 375 (Ser(375)). Ser(375) phosphorylation was suff...
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Morphine induces terminal micro-opioid receptor desensitization by sustained phosphorylation of serine-375
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TN_cdi_proquest_miscellaneous_66793964
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66793964
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ISSN
0261-4189
