Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Apollon (also known as BRUCE or BIRC6) is a large protein containing baculoviral-IAP-repeat (BIR) and ubiquitin-conjugating enzyme (UBC) domains at the amino- and carboxy termini, respectively. Apollon inhibits apoptosis, but its molecular and physiological function remains unclear. Here we report that Apollon binds to, ubiquitinates and facilitate...
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Apollon ubiquitinates SMAC and caspase-9, and has an essential cytoprotection function
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TN_cdi_proquest_miscellaneous_66836925
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66836925
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1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb1159
