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Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat pr...

Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66875795

Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex

About this item

Full title

Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex

Publisher

Berlin/Heidelberg: Springer-Verlag

Journal title

Psychopharmacology, 2009-01, Vol.202 (1-3), p.521-530

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Springer-Verlag

More information

Scope and Contents

Contents

Background and rationale
Genetic variations in catechol-
O
-methyl transferase (COMT) or administration of COMT inhibitors have a robust impact on cognition and executive function in humans. The COMT enzyme breaks down extracellular dopamine (DA) and has a particularly important role in the prefrontal cortex (PFC) where DA transporters are...

Alternative Titles

Full title

Tolcapone enhances food-evoked dopamine efflux and executive memory processes mediated by the rat prefrontal cortex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66875795

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66875795

Other Identifiers

ISSN

0033-3158

E-ISSN

1432-2072

DOI

10.1007/s00213-008-1342-1

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