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Evidence Why Paroxetine Dose Escalation is Not Effective in Major Depressive Disorder: A Randomized...

Evidence Why Paroxetine Dose Escalation is Not Effective in Major Depressive Disorder: A Randomized...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66907311

Evidence Why Paroxetine Dose Escalation is Not Effective in Major Depressive Disorder: A Randomized Controlled Trial With Assessment of Serotonin Transporter Occupancy

About this item

Full title

Evidence Why Paroxetine Dose Escalation is Not Effective in Major Depressive Disorder: A Randomized Controlled Trial With Assessment of Serotonin Transporter Occupancy

Publisher

Cham: Springer International Publishing

Journal title

Neuropsychopharmacology (New York, N.Y.), 2009-03, Vol.34 (4), p.999-1010

Language

English

Formats

Publication information

Publisher

Cham: Springer International Publishing

More information

Scope and Contents

Contents

Dose escalation is often used in depressed patients who fail to respond to standard doses of selective serotonin reuptake inhibitors, but clinical efficacy is equivocal. We aimed to reassess the efficacy of paroxetine dose escalation and quantify whether paroxetine dose escalation increases occupancy of the serotonin transporter (SERT) more than pl...

Alternative Titles

Full title

Evidence Why Paroxetine Dose Escalation is Not Effective in Major Depressive Disorder: A Randomized Controlled Trial With Assessment of Serotonin Transporter Occupancy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66907311

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66907311

Other Identifiers

ISSN

0893-133X

E-ISSN

1740-634X

DOI

10.1038/npp.2008.148

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