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Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with sta...

Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with sta...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66920381

Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings

About this item

Full title

Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings

Publisher

United States: Elsevier Limited

Journal title

Molecular therapy, 2004-10, Vol.10 (4), p.799-816

Language

English

Formats

Publication information

Publisher

United States: Elsevier Limited

More information

Scope and Contents

Contents

We produced lethally irradiated retrovirally GM-CSF-transduced autologous renal tumor cell vaccines (GVAX) from six Japanese patients with stage IV renal cell cancer (RCC). Four patients received GVAX ranging from 1.4 x 10(8) to 3.7 x 10(8) cells on 6-17 occasions. Throughout a total of 48 vaccinations, there were no severe adverse events. After va...

Alternative Titles

Full title

Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_66920381

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66920381

Other Identifiers

ISSN

1525-0016

E-ISSN

1525-0024

DOI

10.1016/j.ymthe.2004.07.001

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