A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 p...
A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Interleukin-18 (IL-18) is a proinflammatory cytokine synthesized as a 24 kDa inactive precursor (pro-IL-18) by several cell types, and is processed to a bioactive molecule of 18 kDa by the proteinases caspase-1 or caspase-4. All ovarian carcinoma cell lines express pro-IL-18, only in some instances coexpress caspase-1, and always express caspase-4;...
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Full title
A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing
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TN_cdi_proquest_miscellaneous_66926031
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66926031
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1208036
