Codon-Specific Translational Defect Caused by a Wobble Modification Deficiency in Mutant tRNA from a...
Codon-Specific Translational Defect Caused by a Wobble Modification Deficiency in Mutant tRNA from a Human Mitochondrial Disease
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United States: National Academy of Sciences
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English
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United States: National Academy of Sciences
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Point mutations in the mitochondrial (mt) tRNA Leu( UUR) gene are responsible for mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), a subgroup of mitochondrial encephalomyopathic diseases. We previously showed that mt tRNA Leu( UUR) with an A3243G or T3271C mutation derived from patients with MELAS are defic...
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Codon-Specific Translational Defect Caused by a Wobble Modification Deficiency in Mutant tRNA from a Human Mitochondrial Disease
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TN_cdi_proquest_miscellaneous_66989329
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66989329
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0405173101
