HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor...
HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation
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Publisher
London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
The high-risk HPV E6 proteins have been shown to direct the degradation of a variety of cellular proteins that contain PDZ domains. Although some of these proteins are involved in regulating processes of cell growth and polarity in
Drosophila
, little is known about their function in higher eukaryotic epithelial cells. In HPV-containing cells...
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HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation
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TN_cdi_proquest_miscellaneous_66995089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_66995089
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1207977
