SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence fo...
SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression
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Author / Creator
Zill, P , Baghai, T C , Zwanzger, P , Schüle, C , Eser, D , Rupprecht, R , Möller, H-J , Bondy, B and Ackenheil, M
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Tryptophan hydroxylase (TPH), being the rate-limiting enzyme in the biosynthesis of serotonin plays a major role as candidate gene in several psychiatric disorders. Recently, a second TPH isoform (TPH2) was identified in mice, which was exclusively present in the brain. In a previous post-mortem study of our own group, we could demonstrate that TPH...
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SNP and haplotype analysis of a novel tryptophan hydroxylase isoform (TPH2) gene provide evidence for association with major depression
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TN_cdi_proquest_miscellaneous_67008230
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67008230
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ISSN
1359-4184
E-ISSN
1476-5578
DOI
10.1038/sj.mp.4001525
