Triggered Amplification by Hybridization Chain Reaction
Triggered Amplification by Hybridization Chain Reaction
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United States: National Academy of Sciences
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Language
English
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United States: National Academy of Sciences
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Contents
We introduce the concept of hybridization chain reaction (HCR), in which stable DNA monomers assemble only upon exposure to a target DNA fragment. In the simplest version of this process, two stable species of DNA hairpins coexist in solution until the introduction of initiator strands triggers a cascade of hybridization events that yields nicked d...
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Full title
Triggered Amplification by Hybridization Chain Reaction
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TN_cdi_proquest_miscellaneous_67016334
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67016334
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ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.0407024101