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Triggered Amplification by Hybridization Chain Reaction

Triggered Amplification by Hybridization Chain Reaction

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67016334

Triggered Amplification by Hybridization Chain Reaction

About this item

Full title

Triggered Amplification by Hybridization Chain Reaction

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2004-10, Vol.101 (43), p.15275-15278

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

We introduce the concept of hybridization chain reaction (HCR), in which stable DNA monomers assemble only upon exposure to a target DNA fragment. In the simplest version of this process, two stable species of DNA hairpins coexist in solution until the introduction of initiator strands triggers a cascade of hybridization events that yields nicked d...

Alternative Titles

Full title

Triggered Amplification by Hybridization Chain Reaction

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67016334

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67016334

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0407024101

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