The 3D nuclear organization of telomeres marks the transition from Hodgkin to Reed–Sternberg cells
The 3D nuclear organization of telomeres marks the transition from Hodgkin to Reed–Sternberg cells
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Author / Creator
Knecht, H , Sawan, B , Lichtensztejn, D , Lemieux, B , Wellinger, R J and Mai, S
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
To get an insight into the transition from mononuclear Hodgkin cells (H cells) to diagnostic multinuclear Reed–Sternberg cells (RS cells), we performed an analysis of the three-dimensional (3D) structure of the telomeres in the nuclei of the Hodgkin cell lines HDLM-2, L-428, L-1236 and lymph node biopsies of patients with Hodgkin's disease. Cellula...
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Full title
The 3D nuclear organization of telomeres marks the transition from Hodgkin to Reed–Sternberg cells
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TN_cdi_proquest_miscellaneous_67017562
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67017562
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ISSN
0887-6924
E-ISSN
1476-5551
DOI
10.1038/leu.2008.314