Molecular mechanisms of caspase regulation during apoptosis
Molecular mechanisms of caspase regulation during apoptosis
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Key Points
The molecular mechanism of activation for a representative effector caspase, caspase-7, is revealed by the conformational changes of the active site that take place after the activation cleavage. The essence of this mechanism is the provision of the L2′ loop, which is released by the activation cleavage and provides crucial support fo...
Alternative Titles
Full title
Molecular mechanisms of caspase regulation during apoptosis
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_miscellaneous_67032018
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67032018
Other Identifiers
ISSN
1471-0072
E-ISSN
1471-0080
DOI
10.1038/nrm1496
