Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of t...
Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene
About this item
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Publisher
Japan: Springer Japan
Journal title
Language
English
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Publication information
Publisher
Japan: Springer Japan
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Scope and Contents
Contents
Background
Although sunitinib malate has shown significant clinical effect on imatinib-resistant gastrointestinal stromal tumors, with acceptable tolerability and improved prognosis for the patients, the mechanism of resistance to the drug is still under investigation.
Methods
We analyzed findings in 8 patients (seven men and one woman, me...
Alternative Titles
Full title
Sunitinib-resistant gastrointestinal stromal tumors harbor cis-mutations in the activation loop of the KIT gene
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Record Identifier
TN_cdi_proquest_miscellaneous_67159608
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67159608
Other Identifiers
ISSN
1341-9625
E-ISSN
1437-7772
DOI
10.1007/s10147-008-0822-y
