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Mechanisms of resistance to Erbitux (anti–epidermal growth factor receptor) combination therapy in p...

Mechanisms of resistance to Erbitux (anti–epidermal growth factor receptor) combination therapy in p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67161531

Mechanisms of resistance to Erbitux (anti–epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells

About this item

Full title

Mechanisms of resistance to Erbitux (anti–epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells

Publisher

United States: Elsevier Inc

Journal title

Journal of gastrointestinal surgery, 2004-12, Vol.8 (8), p.960-970

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

We previously demonstrated that pancreatic adenocarcinoma BxPC-3 xenografts display resistance to treatment with Erbitux, gemcitabine, and radiation, whereas MIA PaCa-2 xenografts are highly sensitive to the same therapy. Here, we elucidate in vitro mechanisms that may explain the observed differential response of epidermal growth factor receptor (...

Alternative Titles

Full title

Mechanisms of resistance to Erbitux (anti–epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67161531

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67161531

Other Identifiers

ISSN

1091-255X

E-ISSN

1873-4626

DOI

10.1016/j.gassur.2004.09.021

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