Cerebral Histamine H1 Receptor Binding Potential Measured with PET Under a Test Dose of Olopatadine,...
Cerebral Histamine H1 Receptor Binding Potential Measured with PET Under a Test Dose of Olopatadine, an Antihistamine, Is Reduced After Repeated Administration of Olopatadine
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United States: Soc Nuclear Med
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English
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United States: Soc Nuclear Med
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Some antihistamine drugs that are used for rhinitis and pollinosis have a sedative effect as they enter the brain and block the H(1) receptor, potentially causing serious accidents. Receptor occupancy has been measured with PET under single-dose administration in humans to classify antihistamines as more sedating or as less sedating (or nonsedating...
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Cerebral Histamine H1 Receptor Binding Potential Measured with PET Under a Test Dose of Olopatadine, an Antihistamine, Is Reduced After Repeated Administration of Olopatadine
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TN_cdi_proquest_miscellaneous_67305221
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67305221
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ISSN
0161-5505
E-ISSN
1535-5667
DOI
10.2967/jnumed.108.058537