Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to inf...
Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to influence the polyol pathway
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Canada: Canadian Society for Clinical Investigation
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English
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Canada: Canadian Society for Clinical Investigation
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Increased flux of glucose via the polyol pathway, oxidative stress and ischaemia lead to the upregulation of the aldose reductase (AR), the key enzyme of the polyol pathway. This adversely affects the organism and can in part be reduced by inhibition of the enzyme.
In this study, we examined the effect of the HMG-CoA-reductase inhibitor atorvast...
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Atorvastatin reduces the expression of aldo-keto reductases in HUVEC and PTEC. A new approach to influence the polyol pathway
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TN_cdi_proquest_miscellaneous_67306115
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67306115
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ISSN
1488-2353
E-ISSN
1488-2353
DOI
10.25011/cim.v32i3.6111
