RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling
RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling
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Publisher
New York, NY: Am Thoracic Soc
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Language
English
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Publisher
New York, NY: Am Thoracic Soc
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Contents
The complex and multifactorial pathogenesis of pulmonary hypertension (PH) involves constriction, remodeling, and in situ thrombosis of pulmonary vessels. Both serotonin (5-HT) and Rho kinase signaling may contribute to these alterations.
To investigate possible links between the 5-HT transporter (5-HTT) and RhoA/Rho kinase pathways, as well as...
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Full title
RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling
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TN_cdi_proquest_miscellaneous_67325759
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67325759
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ISSN
1073-449X
E-ISSN
1535-4970
DOI
10.1164/rccm.200805-691OC