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RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling

RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67325759

RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling

About this item

Full title

RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling

Publisher

New York, NY: Am Thoracic Soc

Journal title

American journal of respiratory and critical care medicine, 2009-06, Vol.179 (12), p.1151-1158

Language

English

Formats

Publication information

Publisher

New York, NY: Am Thoracic Soc

More information

Scope and Contents

Contents

The complex and multifactorial pathogenesis of pulmonary hypertension (PH) involves constriction, remodeling, and in situ thrombosis of pulmonary vessels. Both serotonin (5-HT) and Rho kinase signaling may contribute to these alterations.
To investigate possible links between the 5-HT transporter (5-HTT) and RhoA/Rho kinase pathways, as well as...

Alternative Titles

Full title

RhoA and Rho Kinase Activation in Human Pulmonary Hypertension: Role of 5-HT Signaling

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_miscellaneous_67325759

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_miscellaneous_67325759

Other Identifiers

ISSN

1073-449X

E-ISSN

1535-4970

DOI

10.1164/rccm.200805-691OC

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